TCEB1 Antibody - C-terminal region (OAAB11145)

Catalog No: OAAB11145

Size:400UL

TCEB1 Antibody (C-term) (Cat. #OAAB11145) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the TCEB1 antibody detected the TCEB1 protein (arrow).

TCEB1 is supported by BioGPS gene expression data to be expressed in Jurkat

TCEB1 Antibody (C-term) (OAAB11145)immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TCEB1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Product Info

• Predicted Species Reactivity: Bovine|Human|Mouse|Rat
• Product Format: Liquid PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: IHC-P,WB
• Additional Information: Cellular Location: Nucleus (Probable).
  Tissue Location: Overexpressed in prostate cancer cell line PC- 3 and breast cancer cell line SK-BR-3
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This TCEB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the C-terminal region of human TCEB1.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: Varies by lot. See vial for concentration.
• Intended Use: TCEB1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
• Application Info: WB: 1:1000
  IHC-P: 1:10~50

Target Info

• Gene Symbol: TCEB1
• Alias Symbols: 2610043E24Rik, 2610301I15Rik, AA407206, AI987979, AW049146, elongation factor SIII p15 subunit, elongin 15 kDa subunit, elongin-C, RNA polymerase II transcription factor SIII subunit C, SIII, SIII p15, stromal membrane-associated protein SMAP1B homolog, TCEB1, transcription elongation factor B (SIII), polypeptide 1, transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C), transcription elongation factor B polypeptide 1, transcription elongation factor B subunit 1.
• NCBI Gene Id: 540859|64525|67923|6921
• Protein Name: Elongin-C|elongin-C isoform a [Homo sapiens]|elongin-C isoform b [Homo sapiens]
• Description of Target: SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex) (By similarity). In embryonic stem cells, the elongin BC complex is recruited by EPOP to Polycomb group (PcG) target genes in order generate genomic region that display both active and repressive chromatin properties, an important feature of pluripotent stem cells (By similarity).|SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex) (By similarity). In embryonic stem cells, the elongin BC complex is recruited by EPOP to Polycomb group (PcG) target genes in order generate genomic region that display both active and repressive chromatin properties, an important feature of pluripotent stem cells (PubMed:27863225, PubMed:27863226).|SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex) (PubMed:7821821). In embryonic stem cells, the elongin BC complex is recruited by EPOP to Polycomb group (PcG) target genes in order generate genomic region that display both active and repressive chromatin properties, an important feature of pluripotent stem cells (By similarity).
• Uniprot ID: P83940|P83941|Q15369|Q2KII4
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_001191786.1,NP_001191787.1,NP_001191788.1,NP_001191789.1,NP_001191790.1,NP_001191791.1,NP_001191792.1,NP_001191793.1,NP_005639.1
• Molecular Weight: 12473