Size:100ug
$319.00
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SKU
OADC00242
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TBP Antibody (OADC00242)

Catalog#: OADC00242
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species Reactivity Human
Product Format Liquid. Provided in PBS containing 0.05% azide; purified by ammonium sulphate precipitation followed by dialysis.
Clonality Monoclonal
Isotype IgG1
Host Mouse
Conjugation Unconjugated
Application CHIP
Reconstitution and Storage Store at -20C. Avoid repeated freeze/thaw cycles.
Replacement Item This antibody may replace item sc-124002 from Santa Cruz Biotechnology.
Purification Protein A/G purified
Predicted Homology Based on Immunogen Sequence Mouse
Concentration 8 mg/mL
Datasheets/Manuals Printable datasheet for anti-TBP (OADC00242) antibody
Preservative 0.05% Sodium Azide
Specificity Monoclonal antibody raised in mouse against the amino-terminal domain of human TBP (TATA box binding protein).
Application Info CHIP: 4 - 5 ug/IP
Gene Symbol TBP
Official Gene Full Name TATA-box binding protein
Alias Symbols HDL4, GTF2D, SCA17, TFIID, GTF2D1
NCBI Gene Id 6908;
Protein Name TATA-box-binding protein
Description of Target Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. Two transcript variants encoding different isoforms have been found for this gene.
Swissprot Id P20226
Protein Accession # NP_001165556.1
Nucleotide Accession # NM_001172085.1
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express TBP.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express TBP.
  1. What is the species homology for "TBP Antibody (OADC00242)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "TBP Antibody (OADC00242)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "TBP Antibody (OADC00242)" provided in?

    This item is provided in "Liquid. Provided in PBS containing 0.05% azide; purified by ammonium sulphate precipitation followed by dialysis.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "TBP Antibody (OADC00242)"?

    This target may also be called "HDL4, GTF2D, SCA17, TFIID, GTF2D1" in publications.

  5. What is the shipping cost for "TBP Antibody (OADC00242)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "TBP Antibody (OADC00242)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "TBP Antibody (OADC00242)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "TBP Antibody (OADC00242)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "TBP"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "TBP"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "TBP"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "TBP"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "TBP"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "TBP"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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