TBL1X Antibody - middle region (ARP88707_P050)

Catalog No: ARP88707_P050

Host: Rabbit
Target Name: TBL1X
Sample Tissue: Human PANC1 Whole Cell lysates
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBL1X
• Purification: Affinity purified
• Peptide Sequence: Synthetic peptide located within the following region: AAAAAAAATAAATAATTTSAGVSHQNPSKNREATVNGEENRAHSVNNHAK
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-TBL1X (ARP88707_P050) antibody is Catalog # AAP88707

Target Info

• Gene Symbol: TBL1X
• Gene Full Name: transducin (beta)-like 1X-linked
• Alias Symbols: EBI, TBL1, CHNG8, SMAP55
• NCBI Gene Id: 6907
• Protein Name: F-box-like/WD repeat-containing protein TBL1X
• Description of Target: The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.
• Uniprot ID: O60907-2
• Protein Accession #: NP_001132938.1
• Nucleotide Accession #: NM_001139466.1
• Protein Size (# AA): 526
• Molecular Weight: 57 kDa