TBKBP1 Antibody (OAPB00962)

Catalog No: OAPB00962

Size:100UG

Western blot analysis of Prosapip2 in rat liver tissue lysate with Prosapip2 antibody at 1 ug/mL.

Immunohistochemistry of Prosapip2 in rat liver tissue with Prosapip2 antibody at 5 ug/mL.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. Prosapip2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: Prosapip2 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Immunogen: Prosapip2 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human Prosapip2. The immunogen is located within amino acids 500 - 550 of Prosapip2.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-TBKBP1 (OAPB00962) antibody is Catalog # OEPB03077
• Application Info: Prosapip2 antibody can be used for detection of Prosapip2 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
• Reference: Bouwmeester T, Bauch A, Ruffner H, et al. A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. Nat. Cell Biol.2004; 6:97–105 ;Ryzhakov G and Randow F. SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK. EMBO J.2007; 26:3180–90. ;Meffert MK, Chang JM, Wiltgen BJ, et al. NF-kappa B functions in synaptic signaling and behavior. Nat. Neurosci.2003; 6:1072–78.;Liebau S, Proepper C, Schmidt T, et al. ProSAPiP2, a novel postsynaptic density protein that interacts with ProSAP2/Shank3. Biochem. Biophys. Res Commun.2009; 385:460-5.

Target Info

• Gene Symbol: TBKBP1
• Gene Full Name: TBK1 binding protein 1
• Alias Symbols: ProSAPiP2;SINTBAD;TANK-binding kinase 1-binding protein 1.
• NCBI Gene Id: 9755
• Protein Name: TANK-binding kinase 1-binding protein 1|TANK-binding kinase 1-binding protein 1 [Homo sapiens]
• Description of Target: Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity.
• Uniprot ID: A7MCY6
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_055541
• Nucleotide Accession #: NM_014726.2; XM_005257859.3; XM_005257860.3; XM_005257861.3; XM_005257862.3