TAU Antibody (OAAD00203)

Catalog No: OAAD00203

Size:100 ug

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Clonality: Monoclonal
• Clone: TAU-93
• Isotype: IgG1
• Host: Mouse
• Application: WB, IHC, IP
• Reconstitution and Storage: At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for longer time.
• Immunogen: Bovine microtubule-associated proteins (MAPs).
• Purification: Purified by the goat anti-mouse IgG Affinity chromatography.
• Specificity: Human, mouse, rat.
  No cross reactivity with other proteins.
• Formulation: Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.01mg NaN3 as preservative.
• Application Info: Western blot At 0.5-1ug/ml with the appropriate system to detect Tau in cells and tissues.
  Immunohistochemistry(P) At 1-2ug/ml to detect Tau in formalin fixed and paraffin embedded tissues.
  Other applications have not been tested.
  Optimal dilutions should be determined by end user.
• Storage Buffer: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
• Reference: 1. Andreadis, A.; Brown, W. M.; Kosik, K. S. : Structure and novel exons of the human tau gene.
  Biochemistry 31: 10626-10633, 1992.
  2. Donlon, T. A.; Harris, P.; Neve, R. L. : Localization of microtubule-associated protein tau (MTBT1) to chromosome 17q21. (Abstract) Cytogenet. Cell Genet. 46: 607, 1987.

Target Info

• Gene Symbol: MAPT
• Alias Symbols: TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, tau-40, FTDP-17, PPP1R103
• NCBI Gene Id: 4137
• Protein Name: Microtubule-associated protein tau
• Description of Target: The microtubule-associated proteins (MAPs) coassemble with tubulin into microtubules in vitro.
  Microtubule-associated protein tau appears to be enriched in axons. Tau are composed of 352 to 441 amino acids. The isoforms differ from each other by the presence or absence of 29-amino acid or 58-amino acid inserts located in the N terminus and a 31-amino repeat located in the C terminus. tau is important in establishing and maintaining neuronal morphology and is a major component of the neurofibrillary tangles (NFTs) characteristic of Alzheimer's brain. Microtubule-associated protein tau (MTBT1) is mapped to chromosome 17q21
• Uniprot ID: P10636