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Now Offering Over 102,157 Antibodies & 44,722 Antigens!

TAF15 antibody - N-terminal region (ARP30112_P050)

100 ul
$319.00
In Stock

Conjugation Options

ARP30112_P050-FITC Conjugated

ARP30112_P050-HRP Conjugated

ARP30112_P050-Biotin Conjugated

Gene Symbol:
TAF15
NCBI Gene Id:
8148
Official Gene Full Name:
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
Protein Name:
TATA-binding protein-associated factor 2N
Swissprot Id:
Q92804-2
Protein Accession #:
NP_631961
Nucleotide Accession #:
NM_139215
Alias Symbols:
Npl3, RBP56, TAF2N, TAFII68, hTAFII68
Replacement Item:
This antibody may replace item sc-109061 from Santa Cruz Biotechnology.
Description of Target:
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. Its gene encodes a subunit of TFIID present in a subset of TFIID complexes. Translocations involving chromosome 17 and chromosome 9, where the gene for the nuclear receptor CSMF is located, result in a gene fusion product that is an RNA binding protein associated with a subset of extraskeletal myxoid chondrosarcomas.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a subunit of TFIID present in a subset of TFIID complexes. Translocations involving chromosome 17 and chromosome 9, where the gene for the nuclear receptor CSMF is located, result in a gene fusion product that is an RNA binding protein associated with a subset of extraskeletal myxoid chondrosarcomas. Two transcripts encoding different isoforms have been identified.
Protein Size (# AA):
592
Molecular Weight:
61kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express TAF15.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express TAF15.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human TAF15
Species Reactivity:
Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat, Yeast
Predicted Homology Based on Immunogen Sequence:
Cow: 93%; Dog: 93%; Guinea Pig: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Yeast: 77%
Complete computational species homology data:
Anti-TAF15 (ARP30112_P050)
Peptide Sequence:
Synthetic peptide located within the following region: TDSSYGQNYSGYSSYGQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQN
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
RPA3; RPA2; RPA1; SUZ12; RNF2; EZH2; BMI1; EED; UBD; PRMT8; MED26; UBC; FUS; TPR; TPM2; DDB1; SCARB2; RNF168; TMED9; SAP30BP; NEDD8; CAND1; DCUN1D1; COPS5; COPS6; CUL1; CUL2; CUL3; CUL4A; CUL4B; CUL5; YWHAZ; SIRT7; HIST2H4A; HIST1H3A; HIST2H2AC; CACNA1A;
Blocking Peptide:
For anti-TAF15 (ARP30112_P050) antibody is Catalog # AAP30112 (Previous Catalog # AAPH00288)
Datasheets/Manuals:
Printable datasheet for anti-TAF15 (ARP30112_P050) antibody
Sample Type Confirmation:

TAF15 is supported by BioGPS gene expression data to be expressed in Daudi

Target Reference:
Lee, H.J., et al., (2004) FEBS Lett. 564 (1-2), 188-198
Publications:

Ko, S. Y., Lengyel, E. & Naora, H. The Müllerian HOXA10 gene promotes growth of ovarian surface epithelial cells by stimulating epithelial-stromal interactions. Mol. Cell. Endocrinol. 317, 112-9 (2010). IHC, WB, Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat, Yeast 20048082

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