TACC2 Antibody (OAGA00856)

Catalog No: OAGA00856

Size:100 ul

Sample(30 ug whole cell lysate)
A:H1299
7.5% SDS PAGE
OAGA00856 diluted at 1:1000

Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using TACC2(OAGA00856) antibody at 1:100 dilution.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IHC-FFPE, WB
• Additional Information: Background: Transforming acidic coiled-coil proteins are a conserved family of centrosome- and microtubule-interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is induced by erythropoietin and is thought to affect the progression of breast tumors. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  Positive Controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji
  Cellular Localization: Cytoplasm, Nucleus, Centrosome
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 237 and 293 (O95359) of TACC2
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 0.28 mg/ml
• Application Info: Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)]. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: TACC2
• Gene Full Name: Transforming acidic coiled-coil-containing protein 2
• Alias Symbols: AZU-1, ECTACC
• NCBI Gene Id: 10579
• Protein Name: Transforming acidic coiled-coil-containing protein 2
• Uniprot ID: O95359
• Protein Accession #: NP_008928.1
• Molecular Weight: 119 kDa