Search Antibody, Protein, and ELISA Kit Solutions

TAB2 Antibody - middle region (ARP74274_P050)

100 ul
$289.00
In Stock
Request Bulk Order Quote

Conjugation Options

ARP74274_P050-FITC Conjugated

ARP74274_P050-HRP Conjugated

ARP74274_P050-Biotin Conjugated

Gene Symbol:
TAB2
NCBI Gene Id:
23118
Swissprot Id:
Q9NYJ8-2
Alias Symbols:
TAB2, KIAA0733, MAP3K7IP2,
Replacement Item:
This antibody may replace item sc-398188 from Santa Cruz Biotechnology.
Description of Target:
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein, along with TAB1 and MAP3K7, also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Studies of the related mouse protein indicate that it functions to protect against liver damage caused by chemical stressors. Mutations in this gene cause congenital heart defects, multiple types, 2 (CHTD2). Alternative splicing results in multiple transcript variants.
Protein Size (# AA):
536
Molecular Weight:
58kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express TAB2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express TAB2.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of Human TAB2
Predicted Species Reactivity:
Human
Tested Species Reactivity:
Human
Peptide Sequence:
Synthetic peptide located within the following region: SGSSQSSAHSQYNIQNISTGPRKNQIEIKLEPPQRNNSSKLRSSGPRTSS
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; PIAS3; UBE2I; TRAF6; SUMO2; IRAK1; MAP3K7; TRIM38; SIK1; SIK3; TRIM22; NPM1; CST9L; SLC19A3; env; TAB1; NUMBL; IKBKG; FOSL1; ZBTB16; YWHAZ; VIM; TGM2; PPP2CB; IKBKB; GTF2I; FN1; HSP90AA1; BST2; MALT1; WDR34; APP; ESR1; MAP3K8; AR; TRIM5; TBL1XR1; MBD
Blocking Peptide:
For anti-TAB2 (ARP74274_P050) antibody is Catalog # AAP74274
Datasheets/Manuals:
Printable datasheet for anti-TAB2 (ARP74274_P050) antibody

Product Reviews

Tell us what you think about this item!

Write A Review
    Please, wait...