SYK Antibody (Phospho-Tyr525) (OASG06928)

Catalog No: OASG06928

Size:100 uL

Western Blot using COS7

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Monkey
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human Syk around the phosphorylation site of Y525. Location: 460-540aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Tyr525
• Specificity: Phospho-Syk (Tyr525) Polyclonal Antibody detects endogenous levels of Syk protein only when phosphorylated at Y525.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;

Target Info

• Gene Symbol: SYK
• Gene Full Name: spleen tyrosine kinase
• Alias Symbols: p72-Syk
• NCBI Gene Id: 6850; 20963; 25155
• Description of Target: This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Uniprot ID: P43405, P48025, Q64725
• Molecular Weight: 72 kDa