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Swine H1N1 Neuraminidase Antibody (OAPB00918)
Datasheets/Manuals | Printable datasheet for Swine H1N1 Neuraminidase Antibody (OAPB00918) (OAPB00918) |
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Predicted Species Reactivity | Influenza A Virus|Virus |
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Product Format | Liquid. Swine H1N1 Neuraminidase Antibody is supplied in PBS containing 0.02% sodium azide. |
Clonality | Polyclonal |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay |
Additional Information | Source: Rabbit polyclonal antibody was raised against a synthetic peptide containing the sequence specific to the novel S-OIV A H1N1 strain neuraminidase protein (Genbank accession no. ACQ76308). |
:: | Buffer: Antibody is supplied in PBS containing 0.02% sodium azide. |
Reconstitution and Storage | 2°C to 8°C |
Immunogen | Neuraminidase antibody was raised against a synthetic peptide from the novel swine influenza Neuraminidase protein. This antibody is a cognate pair with product 5247. The immunogen is located within amino acids 50 - 100 of Swine H1N1 Neuraminidase. |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Virus |
Concentration | 1 mg/ml |
Blocking Peptide | For anti-Swine H1N1 Neuraminidase (OAPB00918) antibody is Catalog # OEPB02983 |
Specificity | This antibody is specific for the novel swine influenza neuraminidase and will not recognize the corresponding neuraminidase sequence from the seasonal H1N1 influenza (A/Georgia/20/2006 (H1N1)). |
Application Info | Neuraminidase antibody can be used for the detection of the Neuraminidase protein from the H1N1 strain of swine influenza A in ELISA. It will detect 2 ng of free peptide at 1 ug/ml and will not cross-react with peptide corresponding to the seasonal influenza (H1N1) Neuraminidase. (Optimal dilution should be determined by user) |
Other Applications Image 1 Data | ELISA results using Swine H1N1 Neuraminidase antibody at 1 ug/mL and the blocking and corresponding peptides at 50, 10, 2 and 0 ng/ml. |
Reference | Thompson WW, Shay DK, Weintraub, et al. Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA2003; 289:179-186.;Novel Swine-Origin Influenza A (H1N1) Virus Investigation Team, Dawood FS, Jain S, et al. Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N. Engl. J. Med.2009; 360:2605-15.;Butler D. Swine flu goes global. Nature2009; 458:1082-3.;Morens DM, Taubenberger JK, and Fauci AS. The Persistent Legacy of the 1918 Influenza Virus. N. Engl. J. Med.2009; Jun 29. |
Gene Symbol | Swine H1N1 Neuraminidase |
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Gene Full Name | Neuraminidase |
Protein Name | Neuraminidase|neuraminidase [Influenza A virus (A/California/14/2009(H1N1))] |
Description of Target | Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates. Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release. Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface. These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell. Otherwise, infection would be limited to one round of replication. Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors. May facilitate viral invasion of the upper airways by cleaving the sialic acid moities on the mucin of the airway epithelial cells. Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport. May additionally display a raft-association independent effect on budding. Plays a role in the determination of host range restriction on replication and virulence. Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication. |
Uniprot ID | Q91IA9 |
Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/ACQ76308 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Swine H1N1 Neuraminidase Antibody (OAPB00918)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Influenza A Virus|Virus".
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How long will it take to receive "Swine H1N1 Neuraminidase Antibody (OAPB00918)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "Swine H1N1 Neuraminidase Antibody (OAPB00918)" provided in?
This item is provided in "Liquid. Swine H1N1 Neuraminidase Antibody is supplied in PBS containing 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Swine H1N1 Neuraminidase Antibody (OAPB00918)"?
This target may also be called "" in publications.
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What is the shipping cost for "Swine H1N1 Neuraminidase Antibody (OAPB00918)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Swine H1N1 Neuraminidase Antibody (OAPB00918)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Swine H1N1 Neuraminidase Antibody (OAPB00918)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Swine H1N1 Neuraminidase Antibody (OAPB00918)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "SWINE H1N1 NEURAMINIDASE"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "SWINE H1N1 NEURAMINIDASE"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "SWINE H1N1 NEURAMINIDASE"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "SWINE H1N1 NEURAMINIDASE"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "SWINE H1N1 NEURAMINIDASE"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "SWINE H1N1 NEURAMINIDASE"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.