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Datasheets/Manuals | Printable datasheet for SUV39H2 Antibody (OAAF04584) |
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Predicted Species Reactivity | Human|Mouse |
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Product Format | Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Application | Enzyme-linked immunosorbent assay|Western blot |
Reconstitution and Storage | -20°C |
Immunogen | The antiserum was produced against synthesized peptide derived from human SUV39H2. |
Purification | The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen. |
Specificity | SUV39H2 antibody detects endogenous levels of total SUV39H2. |
Dilution | The optimal working dilution should be determined by the end user. |
Application Info | WB 1:500~1000 ELISA 1:10000 |
Reference | Sugano S., Nat. Genet. 36:40-45(2004). Venter J.C., Submitted (SEP-2005). Schupp I., BMC Genomics 8:399-399(2007). |
Gene Symbol | SUV39H2 |
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Gene Full Name | SUV39H2 histone lysine methyltransferase |
Alias Symbols | H3-K9-HMTase 2;histone H3-K9 methyltransferase 2;histone methyltransferase SUV39H2;histone-lysine N-methyltransferase SUV39H2;KMT1B;lysine N-methyltransferase 1B;su(var)3-9 homolog 2;suppressor of variegation 3-9 homolog 2. |
NCBI Gene Id | 79723 |
Protein Name | Histone-lysine N-methyltransferase SUV39H2 |
Description of Target | Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher-order chromatin organization during spermatogenesis. Recruited by the large PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1, contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation. |
Uniprot ID | Q9H5I1 |
Protein Accession # | NP_001180353.1 |
Molecular Weight | 46 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "SUV39H2 Antibody (OAAF04584)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
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How long will it take to receive "SUV39H2 Antibody (OAAF04584)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "SUV39H2 Antibody (OAAF04584)" provided in?
This item is provided in "Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "SUV39H2 Antibody (OAAF04584)"?
This target may also be called "H3-K9-HMTase 2;histone H3-K9 methyltransferase 2;histone methyltransferase SUV39H2;histone-lysine N-methyltransferase SUV39H2;KMT1B;lysine N-methyltransferase 1B;su(var)3-9 homolog 2;suppressor of variegation 3-9 homolog 2." in publications.
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What is the shipping cost for "SUV39H2 Antibody (OAAF04584)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "SUV39H2 Antibody (OAAF04584)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "SUV39H2 Antibody (OAAF04584)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "46 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "SUV39H2 Antibody (OAAF04584)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "SUV39H2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "SUV39H2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "SUV39H2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "SUV39H2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "SUV39H2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "SUV39H2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.