SUMO4 Antibody (Phospho-M55 Wild type) (OAAB08931)

Catalog No: OAAB08931

Size:400ul

Western blot analysis of SUMO4 Antibody (M55 Wild type) (Cat. #OAAB08931) in HepG2 cell line lysate (35ug/lane). SUMO4 wild type (arrow) was detected using the purified Pab.

SUMO4 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with SUMO4 antibody (M55 Wild type) (Cat.#OAAB08931), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, IHC
• Additional Information: Precautions: SUMO4 Antibody (M55 Wild type) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I
  Tissue Location: Expressed mainly in adult and embryonic kidney. Expressed at various levels in immune tissues, with the highest expression in the lymph node and spleen
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This SUMO4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-63 amino acids from human SUMO4.
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Sample Type Confirmation:

  SUMO4 is strongly supported by BioGPS gene expression data to be expressed in HepG2

• Application Info: WB: 1:1000
  IHC-P: 1:50~100

Target Info

• Gene Symbol: SUMO4
• Alias Symbols: IDDM5, SMT3H4, SUMO-4, dJ281H8.4
• NCBI Gene Id: 387082
• Protein Name: Small ubiquitin-related modifier 4
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: Q6EEV6
• Protein Accession #: NP_001002255.1
• Molecular Weight: 10685 Da