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Datasheets/Manuals | Printable datasheet for anti-STAU1 (ARP40536_P050) antibody |
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Tested Species Reactivity | Human |
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Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Clonality | Polyclonal |
Host | Rabbit |
Application | WB |
Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human STAU1 |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92% |
Peptide Sequence | Synthetic peptide located within the following region: NFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELK |
Concentration | 0.5 mg/ml |
Blocking Peptide | For anti-STAU1 (ARP40536_P050) antibody is Catalog # AAP40536 (Previous Catalog # AAPS00708) |
Sample Type Confirmation | STAU1 is strongly supported by BioGPS gene expression data to be expressed in 721_B |
Gene Symbol | STAU1 |
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Gene Full Name | Staufen, RNA binding protein, homolog 1 (Drosophila) |
Alias Symbols | STAU, PPP1R150 |
NCBI Gene Id | 6780 |
Protein Name | Double-stranded RNA-binding protein Staufen homolog 1 |
Description of Target | STAU1(Staufen) is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR. |
Uniprot ID | O95793 |
Protein Accession # | EAW75670 |
Nucleotide Accession # | NM_001037328 |
Protein Size (# AA) | 317 |
Molecular Weight | 35kDa |
Protein Interactions | LONRF1; GLRX3; ZMAT3; NXT1; SPRTN; MATR3; EIF4A3; NUP155; PRDX6; NPEPPS; DDX23; DDX21; AIFM1; INA; ATP6V0D1; SART1; RPL14; AP3D1; CPNE3; IQGAP1; PABPC4; EIF3D; EIF3B; EIF3A; PRKRA; KHSRP; IRS4; SLC25A11; SMC1A; PABPN1; DDX39B; TUBA1A; MOGS; YWHAZ; XPO1; V |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "STAU1 Antibody - N-terminal region (ARP40536_P050)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".
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How long will it take to receive "STAU1 Antibody - N-terminal region (ARP40536_P050)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
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What buffer format is "STAU1 Antibody - N-terminal region (ARP40536_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "STAU1 Antibody - N-terminal region (ARP40536_P050)"?
This target may also be called "STAU, PPP1R150" in publications.
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What is the shipping cost for "STAU1 Antibody - N-terminal region (ARP40536_P050)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "STAU1 Antibody - N-terminal region (ARP40536_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "STAU1 Antibody - N-terminal region (ARP40536_P050)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "35kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "STAU1 Antibody - N-terminal region (ARP40536_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "STAU1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "STAU1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "STAU1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "STAU1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "STAU1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "STAU1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.