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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
Datasheets/Manuals | Printable datasheet for OAAQ00015 |
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Tested Species Reactivity | Human, Mouse |
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Predicted Species Reactivity | Mouse, Rat |
Product Format | Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA. |
Clonality | Monoclonal |
Clone | Stat6Y641-G12 |
Isotype | Rabbit IgG1k |
Host | Rabbit |
Conjugation | PE: Phycoerythrin |
Application | FC |
Reconstitution and Storage | 2-8C |
Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Tyr641 of human phospho Stat6 |
Purification | Protein A+G |
Target Post-Translational Modification | Phospho-Tyr641 |
Application Info | For flow cytometric staining, the suggested use of this reagent is 5 uL per million cells or 5 uL per 100 uL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application. |
Reference | Kaplan MH, Schindler U, Smiley ST, and Grusby MJ. (1996) Immunity. 4:313-319. Demicco EG, Harms PW, Patel RM, et al. (2015) American Journal of Clinical Pathology. 143:672-682. Wick KR, and Berton MT. (2000) Molecular Immunology. 37:641-652. |
Gene Symbol | STAT6 |
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Gene Full Name | signal transducer and activator of transcription 6 |
Alias Symbols | STAT6B, STAT6C, D12S1644, IL-4-STAT |
NCBI Gene Id | 6778 |
Protein Name | signal transducer and activator of transcription 6 |
Description of Target | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants. |
Uniprot ID | P42226 |
Protein Accession # | NP_001171549.1 |
Nucleotide Accession # | NM_001178078.1 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Human STAT6 Antibody : PE (Phospho-Tyr641) (OAAQ00015)"?
The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Mouse, Rat".
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How long will it take to receive "Human STAT6 Antibody : PE (Phospho-Tyr641) (OAAQ00015)"?
This item is available "Domestic: within 1 week delivery | International: 1 week".
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What buffer format is "Human STAT6 Antibody : PE (Phospho-Tyr641) (OAAQ00015)" provided in?
This item is provided in "Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Human STAT6 Antibody : PE (Phospho-Tyr641) (OAAQ00015)"?
This target may also be called "STAT6B, STAT6C, D12S1644, IL-4-STAT" in publications.
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What is the shipping cost for "Human STAT6 Antibody : PE (Phospho-Tyr641) (OAAQ00015)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Human STAT6 Antibody : PE (Phospho-Tyr641) (OAAQ00015)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Human STAT6 Antibody : PE (Phospho-Tyr641) (OAAQ00015)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Human STAT6 Antibody : PE (Phospho-Tyr641) (OAAQ00015)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "STAT6"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "STAT6"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "STAT6"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "STAT6"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "STAT6"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "STAT6"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.