STAT6 Antibody (OASG06897)

Catalog No: OASG06897

Size:100 uL

Western Blot using HeLa

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC, IP
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human Stat6 around the non-phosphorylation site of Y641. Location: 580-660aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: Stat6 Polyclonal Antibody detects endogenous levels of Stat6 protein.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; IP 1:200-500; ELISA 1:20000;

Target Info

• Gene Symbol: STAT6
• Gene Full Name: signal transducer and activator of transcription 6, interleukin-4 induced
• Alias Symbols: STAT6B, STAT6C, D12S1644, IL-4-STAT
• NCBI Gene Id: 6778; 20852;
• Description of Target: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
• Uniprot ID: P42226, P52633
• Molecular Weight: 94 kDa