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- $55: Antibody & Protein in US
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Datasheets/Manuals | Printable datasheet for STAT5B Antibody (OACA02429) (OACA02429) |
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Predicted Species Reactivity | Human |
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Product Format | Liquid |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Chromatin immunoprecipitation|Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot |
Reconstitution and Storage | -20°C or -80°C |
Immunogen | Recombinant Human Signal transducer and activator of transcription 5B protein (40-280AA) |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Human |
Specificity | Human |
Formulation | Provided in PBS, pH 7.3, 50% Glycerol, 0.02% Sodium Azide |
Application Data | WB:1:500-2000, IHC:1:20-1:200 |
Reference | [1] A Novel Missense Mutation in the SH2 Domain of the STAT5B Gene Results in a transcriptionally inactive STAT5b associated with severe IGF-I deficiency, immune dysfunction, and lack of pulmonary disease. Scaglia P.A., Martinez A.S., Feigerlova E., Bezrodnik L., Gaillard M.I., Di Giovanni D., Ballerini M.G., Jasper H.G., Heinrich J.J., Fang P., Domene H.M., Rosenfeld R.G., Hwa V. J. Clin. Endocrinol. Metab. 97:E830-839 (2012). [2] Growth hormone insensitivity associated with a STAT5b mutation. Kofoed E.M., Hwa V., Little B., Woods K.A., Buckway C.K., Tsubaki J., Pratt K.L., Bezrodnik L., Jasper H., Tepper A., Heinrich J.J., Rosenfeld R.G.N. Engl. J. Med. 349:1139-1147 (2003). [3] Mechanisms of STAT protein activation by oncogenic KIT mutants in neoplastic mast cells. Chaix A., Lopez S., Voisset E., Gros L., Dubreuil P., De Sepulveda P.J. Biol. Chem. 286:5956-5966 (2011). |
Gene Symbol | STAT5B |
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Gene Full Name | signal transducer and activator of transcription 5B |
Alias Symbols | GHISID2;signal transducer and activator of transcription 5B;STAT5;transcription factor STAT5B. |
NCBI Gene Id | 6777 |
Protein Name | Signal transducer and activator of transcription 5B |
Description of Target | Carries out a dual function: signal transduction and activation of transcription (PubMed:29844444). Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation. |
Uniprot ID | P51692 |
Protein Accession # | NP_036580.2 |
Nucleotide Accession # | NM_012448.3 |
Protein Size (# AA) | 787 |
Molecular Weight | 90 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "STAT5B Antibody (OACA02429)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "STAT5B Antibody (OACA02429)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "STAT5B Antibody (OACA02429)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "STAT5B Antibody (OACA02429)"?
This target may also be called "GHISID2;signal transducer and activator of transcription 5B;STAT5;transcription factor STAT5B." in publications.
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What is the shipping cost for "STAT5B Antibody (OACA02429)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "STAT5B Antibody (OACA02429)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "STAT5B Antibody (OACA02429)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "90 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "STAT5B Antibody (OACA02429)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "STAT5B"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "STAT5B"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "STAT5B"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "STAT5B"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "STAT5B"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "STAT5B"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.