STAT4 Antibody (OACA07060)

Catalog No: OACA07060

Immunohistochemistry of paraffin-embedded human cervical cancer at dilution 1:100

Immunohistochemistry of paraffin-embedded human cervical cancer at dilution 1:100

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunohistochemistry
• Reconstitution and Storage: -20°C or -80°C
• Immunogen: Recombinant Human Signal transducer and activator of transcription 4 protein (569-748AA)
• Purification: Affinity Purified
• Preservative: 0.02% sodium azide
• Formulation: PBS with, 50% glycerol, pH7.3.
• Reference: [1]"STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus."Remmers E.F., Plenge R.M., Lee A.T., Graham R.R., Hom G., Behrens T.W., de Bakker P.I.W., Le J.M., Lee H.-S., Batliwalla F., Li W., Masters S.L., Booty M.G., Carulli J.P., Padyukov L., Alfredsson L., Klareskog L., Chen W.V. Gregersen P.K.N. Engl. J. Med. 357:977-986(2007). [2]"The consensus coding sequences of human breast and colorectal cancers." Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. Velculescu V.E. Science 314:268-274(2006). [3]"Cutting edge: autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-alpha in lupus patients in vivo."Kariuki S.N., Kirou K.A., MacDermott E.J., Barillas-Arias L., Crow M.K., Niewold T.B.J. Immunol. 182:34-38(2009).

Target Info

• Gene Symbol: STAT4
• Gene Full Name: signal transducer and activator of transcription 4
• Alias Symbols: signal transducer and activator of transcription 4;signal transducer and activator of transcription 4 variant 3;SLEB11.
• NCBI Gene Id: 6775
• Protein Name: Signal transducer and activator of transcription 4
• Description of Target: Carries out a dual function: signal transduction and activation of transcription. Involved in IL12 signaling.
• Uniprot ID: Q14765
• Protein Accession #: NP_001230764
• Nucleotide Accession #: NM_001243835