ST14 Recombinant Protein (OPCD07205)

Catalog No: OPCD07205

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Arg607-Asn852
  Subcellular Location: Membrane
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 97%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: ST14
• Gene Full Name: ST14 transmembrane serine protease matriptase
• Alias Symbols: ARCI11;CAP3;channel-activating protein 3;HAI;Matriptase;membrane-type serine protease 1;MTSP1;MT-SP1;prostamin;PRSS14;serine protease 14;serine protease TADG-15;SNC19;suppression of tumorigenicity 14 (colon carcinoma);suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin);suppressor of tumorigenicity 14 protein;TADG15;TMPRSS14;tumor associated differentially expressed gene 15 protein;Tumor-associated differentially-expressed gene 15 protein.
• NCBI Gene Id: 6768
• Protein Name: Suppressor of tumorigenicity 14 protein
• Description of Target: Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing.
• Uniprot ID: Q9Y5Y6
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/AAH30532.1
• Protein Size (# AA): Arg607~Asn852
• Molecular Weight: 33kDa