ST13 Antibody (OAEC04563)

Catalog No: OAEC04563

Size:100 ug/100 ul

Western blot analysis using ST13 mouse mAb against A431 (1), HEK293 (2), Hela (3), HepG2 (4), Jurkat (5), K562 (6), L121O (7) and MCF-7 (8) cell lysate.

Immunohistochemical analysis of paraffin-embedded human lung cancer (A), colon cancer (B) using ST13 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded human Thyroid tissues using ST13 mouse mAb

Product Info

• Predicted Species Reactivity: Human
• Product Format: Ascitic fluid containing 0.03% sodium azide
• Clonality: Monoclonal
• Clone: 3B10
• Isotype: IgG1
• Host: Mouse
• Application: WB, IHC, IF
• Reconstitution and Storage: Store at 4C, for long term storage, store at -20C.
• Immunogen: Purified recombinant fragment of human ST13 expres sed in EColi.
• Concentration: 1 mg/ml
• Application Info: WB: 1/500 - 1/2000
  IHC: 1/200 - 1/1000
  IF: 1/200 - 1/1000
  ELISA: 1/10000
  

Target Info

• Gene Symbol: ST13
• Gene Full Name: suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
• Alias Symbols: HIP, HOP, P48, AAG2, SNC6, HSPABP, FAM10A1, FAM10A4, HSPABP1, PRO0786
• NCBI Gene Id: 6767
• Description of Target: ST13 (suppression of tumorigenicity protein 13), also known as Hip (HSP70-interacting protein), is one of several co-chaperones that regulate activities of the HSP70 chaperone fam ily. The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPas e domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 fam ily. B y collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis.
• Uniprot ID: P50502
• Molecular Weight: 48 kDa