SSX2 Antibody - middle region : HRP (ARP51721_P050-HRP)

Catalog No: ARP51721_P050-HRP

Size:100ul

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: HRP: Horseradish Peroxidase
• Application: WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SSX2
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human: 100%
• Peptide Sequence: Synthetic peptide located within the following region: TFGRLQGISPKIMPKKPAEEG
  NDSEEVPEASGPQNDGKELCPPGKPTTS
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-SSX2 (ARP51721_P050-HRP) antibody is Catalog # AAP51721

Target Info

• Gene Symbol: SSX2
• Alias Symbols: SSX, HD21, CT5.2, CT5.2A, HOM-MEL-40
• NCBI Gene Id: 6757
• Protein Name: Protein SSX2
• Description of Target: SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
• Uniprot ID: Q16385-2
• Protein Accession #: NP_783629
• Nucleotide Accession #: NM_175698
• Protein Size (# AA): 223
• Molecular Weight: 24kDa
• Protein Interactions: KRT40; SSX2IP; RAB3IP; SYCE1; ZMIZ2; MAGEC2; AKAP9; ZBED1; TAX1BP1; BLZF1; SUZ12; EED; SMARCA5; TLE1; SMARCA2; HDAC2; HDAC1; EZH2; ATF2; RNF2;