SRY Recombinant Protein (OPCD07197)

Catalog No: OPCD07197

SRY Recombinant Protein (OPCD07197) using SDS-PAGE

SRY Recombinant Protein (OPCD07197) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Isoelectric Point: 9.6
  Residues: Met1-Leu204
  Subcellular Location: Nucleus speckle, Cytoplasm
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: SRY
• Gene Full Name: sex determining region Y
• Alias Symbols: essential protein for sex determination in human males;sex-determining region on Y;sex-determining region Y protein;SRXX1;SRXY1;TDF;TDY;Testis-determining factor;testis-determining factor on Y;truncated sex-determining region Y protein.
• NCBI Gene Id: 6736
• Protein Name: Sex-determining region Y protein
• Description of Target: Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.
• Uniprot ID: Q05066
• Protein Accession #: NP_003131.1
• Nucleotide Accession #: NM_003140.2
• Protein Size (# AA): Met1~Leu204
• Molecular Weight: 28kDa