SRP72 Antibody - middle region (AVARP09038_P050)

Catalog No: AVARP09038_P050

WB Suggested Anti-SRP72 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: PANC1 cell lysateThere is BioGPS gene expression data showing that SRP72 is expressed in PANC1

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SRP72
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 80%
• Peptide Sequence: Synthetic peptide located within the following region: GDSQPKEQGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRG
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-SRP72 (AVARP09038_P050) antibody is Catalog # AAP30615 (Previous Catalog # AAPP01268)
• Sample Type Confirmation:

  There is BioGPS gene expression data showing that SRP72 is expressed in PANC1

• Reference: Iakhiaeva,E., (2008) RNA 14 (6), 1143-1153

Target Info

• Gene Symbol: SRP72
• Gene Full Name: Signal recognition particle 72kDa
• Alias Symbols: BMFF, BMFS1, HEL103
• NCBI Gene Id: 6731
• Protein Name: Signal recognition particle 72 kDa protein
• Description of Target: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP72 binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.
• Uniprot ID: O76094
• Protein Accession #: NP_008878
• Nucleotide Accession #: NM_006947
• Protein Size (# AA): 671
• Molecular Weight: 74kDa
• Protein Interactions: STAU1; LIN28A; TARBP2; RNF2; KIF21A; MLF2; SOX2; METTL18; UBC; SKIL; SRP68; CAND1; CUL3; SIRT7; FCHSD2; HDGF; MEPCE; RPAP1; HNRNPA1; CASP6; CASP3;