SRF Antibody (Phospho-Ser103) (OASG06818)

Catalog No: OASG06818

Size:100 uL

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human SRF around the phosphorylation site of S103. Location: 40-120aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Ser103
• Specificity: Phospho-SRF (S103) Polyclonal Antibody detects endogenous levels of SRF protein only when phosphorylated at S103.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;

Target Info

• Gene Symbol: SRF
• Gene Full Name: serum response factor
• Alias Symbols: MCM1
• NCBI Gene Id: 6722; 20807;
• Description of Target: This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene.
• Uniprot ID: P11831, Q9JM73
• Molecular Weight: 51 kDa