SRC Antibody (Phospho-Tyr419) (OASG01882)

Catalog No: OASG01882

Size:100 uL

Western Blot using COLO205

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human c-Src around the phosphorylation site of Y419. Location: 360-440aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Tyr419
• Specificity: Phospho-c-Src (Tyr419) Polyclonal Antibody detects endogenous levels of c-Src protein only when phosphorylated at Y419.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;

Target Info

• Gene Symbol: SRC
• Gene Full Name: SRC proto-oncogene, non-receptor tyrosine kinase
• Alias Symbols: ASV, SRC1, THC6, c-SRC, p60-Src
• NCBI Gene Id: 6714; 20779;
• Description of Target: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
• Uniprot ID: P12931, P05480, Q9WUD9
• Molecular Weight: 60 kDa