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Catalog No: ARP32475_P050
Price: $0.00
SKU
ARP32475_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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Datasheets/ManualsPrintable datasheet for anti-SRC (ARP32475_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human SRC
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 85%; Dog: 92%; Guinea Pig: 92%; Human: 100%; Mouse: 100%; Rabbit: 77%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: MGSNKSKPKDASQRRRSLEPAENVHGAGGGAFPASQTPSKPASADGHRGP
Concentration0.5 mg/ml
Blocking PeptideFor anti-SRC (ARP32475_P050) antibody is Catalog # AAP32475 (Previous Catalog # AAPP03474)
ReferencePechkovsky,D.V., (2008) J. Biol. Chem. 283 (19), 12898-12908
Gene SymbolSRC
Gene Full NameV-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
Alias SymbolsASV, SRC1, THC6, c-SRC, p60-Src
NCBI Gene Id6714
Protein NameProto-oncogene tyrosine-protein kinase Src
Description of TargetThis gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. SRC protein is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Uniprot IDP12931
Protein Accession #NP_938033
Nucleotide Accession #NM_198291
Protein Size (# AA)536
Molecular Weight60kDa
Protein InteractionsPSMB9; POLR2L; POLR2K; POLR2J; POLR2I; POLR2H; POLR2G; POLR2F; POLR2E; POLR2D; POLR2C; POLR2B; POLR2A; NEDD4; MAPT; ESR1; CA3; ARRB2; UBC; SRC; SPRR2A; IKBKG; CBLC; ZNF658B; TLR4; RGS16; PTGER4; EGFR; ARRB1; TNFRSF1A; KHDRBS1; SYK; CD44; ENO1; ANXA7; PIK3
  1. What is the species homology for "SRC Antibody - N-terminal region (ARP32475_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit".

  2. How long will it take to receive "SRC Antibody - N-terminal region (ARP32475_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "SRC Antibody - N-terminal region (ARP32475_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "SRC Antibody - N-terminal region (ARP32475_P050)"?

    This target may also be called "ASV, SRC1, THC6, c-SRC, p60-Src" in publications.

  5. What is the shipping cost for "SRC Antibody - N-terminal region (ARP32475_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "SRC Antibody - N-terminal region (ARP32475_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "SRC Antibody - N-terminal region (ARP32475_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "60kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "SRC Antibody - N-terminal region (ARP32475_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "SRC"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "SRC"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "SRC"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "SRC"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "SRC"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "SRC"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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