Catalog No: OPPA02366
Size:5UG
Price: $75.00
SKU
OPPA02366
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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- Email: info@avivasysbio.com
Shipping Info:
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
Datasheets/Manuals | Printable datasheet for OPPA02366 |
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Predicted Species Reactivity | Human |
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Product Format | SQSTM1 Human solution containing 20mM Trsi HCL pH-8, 1mM DTT and 10% glycerol. Physical appearance: Sterile filtered colorless solution. |
Host | E. Coli |
:: | Product Introduction: SQSTM1 is an adapter protein which binds ubiquitin and mediates the activation of NFKB1 by TNF-a, NGF and IL-1. SQSTM1 is involved in titin/TTN downstream signaling in muscle cells. SQSTM1 controls signaling cascades through ubiquitination. SQSTM1 participates in cell differentiation, apoptosis, immune response and regulation of K(+) channels. Mutations in UBA domain of the SQSTM1 protein cause Paget's disease because the UBA is essential for aggregate sequestration and cell survival. Product Description: SQSTM1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 264 amino acids (1-356 a.a.) and having a molecular mass of 39.7 kDa. SQSTM1 protein is fused to a 8 amino acid His-Tag at C-terminus and purified by standard chromatography. |
Reconstitution and Storage | SQSTM1 human although stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles. |
Purity | Greater than 90% as determined by SDS-PAGE. |
Peptide Sequence | MAMSYVKDDI FRIYIKEKKE CRRDHRPPCA QEAPRNMVHP NVICDGCNGP VVGTRYKCSV CPDYDLCSVC EGKGLHRGHT KLAFPSPFGH LSEGFSHSRW LRKVKHGHFG WPGWEMGPPG NWSPRPPRAG EARPGPTAES ASGPSEDPSV NFLKNVGESV AAALSPLGIE VDIDVEHGGK RSRLTPVSPE SSSTEEKSSS QPSSCCSDPS KPGGNVEGAT QSLAEQMRKI ALESEGRPEE QMESDNCSGG DDDWTHLSSK EVDPSTGELQ SLQMPESEGP SSLDPSQEGP TGLKEAALYP HLPPEADPRL IESLSQMLSM GFSDEGGWLT RLLQTKNYDI GAALDTIQYS KHPPPLLEHH HHHH. |
Gene Symbol | SQSTM1 |
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Alias Symbols | p60, p62, A170, DMRV, OSIL, PDB3, ZIP3, p62B, NADGP, FTDALS3 |
NCBI Gene Id | 8878 |
Protein Name | Sequestosome-1 |
Description of Target | Recombinant Human Sequestosome 1 |
Uniprot ID | Q13501 |
Protein Accession # | NP_001135770.1 |
Protein Size (# AA) | Recombinant |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
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