SPTLC1 Recombinant Protein (OPCD07187)

Catalog No: OPCD07187

SPTLC1 Recombinant Protein (OPCD07187) using SDS-PAGE

SPTLC1 Recombinant Protein (OPCD07187) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Asp143-Leu473
  Subcellular Location: Membrane
  Predicted isoelectric point: 5.8
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/ml (prior to lyoph)
• Purity: > 90%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Sptlc1
• Gene Full Name: serine palmitoyltransferase, long chain base subunit 1
• Alias Symbols: AW552086;C77762;E030036H05;Lcb;Lcb1;long chain base biosynthesis protein 1;serine palmitoyltransferase 1;serine-palmitoyl-CoA transferase 1;Sp;SPT1.
• NCBI Gene Id: 268656
• Protein Name: Serine palmitoyltransferase 1
• Description of Target: Serine palmitoyltransferase (SPT). The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates. The SPTLC1-SPTLC2-SPTSSB complex displays a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme has the ability to use a broader range of acyl-CoAs (By similarity).
• Uniprot ID: O35704
• Protein Accession #: NP_033295.2
• Nucleotide Accession #: NM_009269.2
• Protein Size (# AA): Asp143~Leu473
• Molecular Weight: 40kDa