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SPRY4 Antibody (OAAB04476)

400ul
$390.00
In Stock
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Gene Symbol:
SPRY4
NCBI Gene Id:
81848
Protein Name:
Protein sprouty homolog 4
Swissprot Id:
Q9C004
Protein Accession #:
NP_001120968.1
Alias Symbols:
Protein sprouty homolog 4, Spry-4, SPRY4
Replacement Item:
This antibody may replace item sc-18607 from Santa Cruz Biotechnology.
Molecular Weight:
32541 Da
Host:
Rabbit
Clonality:
Polyclonal
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Application:
WB, FC, IHC-P
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express SPRY4.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express SPRY4.
Immunogen:
This SPRY4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-56 amino acids from human SPRY4.
Predicted Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Human
Product Format:
Liquid. PBS with 0.09% (W/V) sodium azide.
Reconstitution and Storage:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Datasheets/Manuals:
Printable datasheet for anti-SPRY4 antibody - OAAB04476
Sample Type Confirmation:

SPRY4 is supported by BioGPS gene expression data to be expressed in K562

Isotype:
Rabbit Ig
Intended Use:
For research use only and not for use in diagnostic or therapeutic procedures.
Application Info:
WB: 1:1000
IHC-P: 1:10~50
FC: 1:10~50
:::
Function: Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras. Inhibits Ras-independent, but not Ras-dependent, activation of RAF1.
Cellular Location: Cytoplasm. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side

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