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SPRY1 Antibody (OAEB02388)

100 ug
$349.00
In Stock
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Predicted Species Reactivity:
Dog
Product Format:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Clonality:
Polyclonal
Host:
Goat
Application:
ELISA, WB, IHC
Additional Information:
Reactivity Info: Tested: Human, Mouse; Expected: Human
Reconstitution and Storage:
Aliquot and store at -20C. Minimize freezing and thawing.
Gene Symbol:
SPRY1
NCBI Gene Id:
10252
Protein Name:
Protein sprouty homolog 1
Swissprot Id:
O43609
Protein Accession #:
NP_005832.1
Replacement Item:
This antibody may replace item sc-100861 from Santa Cruz Biotechnology.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express SPRY1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express SPRY1.
Predicted Homology Based on Immunogen Sequence:
Dog: 100%
Complete computational species homology data:
SPRY1 Antibody (OAEB02388)
Peptide Sequence:
CPSRGQGKPS
Datasheets/Manuals:
Printable datasheet for anti-SPRY1 antibody - OAEB02388
Purity:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Application Info:
Peptide ELISA: antibody detection limit dilution 1:16000.
Western Blot: This product has been successfully used in ERMS cells (PMID: 20068162). Recommended concentration: 1-3ug/ml.
Immunohistochemistry: This product has been successfully used by anonymous customers in paraffin embedded Mouse Brain, showing nuclear staining. Recommended concentration: 1-3ug/ml.
Target Reference:
* Schaaf G, Hamdi M, Zwijnenburg D, Lakeman A, Geerts D, Versteeg R, Kool M.; Silencing of SPRY1 triggers complete regression of rhabdomyosarcoma tumors carrying a mutated RAS gene.; Cancer Res. 2010 Jan 15;70(2):762-71. Epub 2010 Jan 12.; Pubmed 20068162
* Hanafusa H, Torii S, Yasunaga T, Matsumoto K, Nishida E.; Shp2, an SH2-containing protein-tyrosine phosphatase, positively regulates receptor tyrosine kinase signaling by dephosphorylating and inactivating the inhibitor Sprouty.; J Biol Chem. 2004 May 28;279(22):22992-5.; Pubmed 15031289

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