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Catalog No: OOPA00058 (Formerly GWB-BSP074)
Size:2ug
Price: $100.00
SKU
OOPA00058
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SPP1 Protein (OOPA00058)

Datasheets/ManualsPrintable datasheet for OOPA00058
Product Info
Product FormatSterile Filtered colorless solution.
HostHEK293 cells.
::Product Introduction: Osteopontin is a glycoprotein that was first identified in osteoblasts and is involved in bone remodeling, immune functions in fibroblasts, macrophages, and lymphocytes during inflammation and wound healing. SPP1 binds tightly to hydroxyapatite. SPP1 forms an integral part of the mineralized matrix. SPP1 is vital to cell-matrix interaction. Secreted Phosphoprotein-1 protects against cardiac ischemia-reperfusion injury via late preconditioning. Expression of both Ostepontin and CD44 in hepatocellular carcinoma is linked with advanced tumor stage and contributes to prognosis information. SPP1 is the most over-expressed gene in intrahepatic cholangiocarcinoma. Secreted Phosphoprotein-1 overexpression is related with interstitial lung diseases.
Product Description: Osteopontin Human Recombinant is a single, glycosylated, polypeptide chain produced in HEK293 cells, is a full length protein (amino acids 17-314) fused with a polyhistidine tag at the C-terminus, having a total calculated molecular mass of 34.5kDa (The actual molecular mass may be approximately 60-65kDa in SDS-PAGE under reducing conditions due to glycosylation). Osteopontin is purified by proprietary chromatographic techniques.
Reconstitution and StorageStore at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. Please avoid freeze thaw cycles.
PurityGreater than 90.0% as determined by SDS-PAGE.
Peptide SequenceIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQN LLAPQNAVSSEETNDFKQETLPSKSNESHDHMDDMDD EDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSD ESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVY GLRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYK AIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEF HSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN HHHHHH.
FormulationOsteopontin is supplied in 50mM Tris, 300mM NaCl and 10% Glycerol, pH 7.5.
PurificationGreater than 90.0% as determined by SDS-PAGE.
Gene SymbolSPP1
Alias SymbolsSecreted Phosphoprotein-1, OPN, BNSP, BSPI, ETA-1, MGC110940, SPP-1, Osteopontin, Bone sialoprotein 1, Urinary stone protein, Nephropontin, Uropontin, SPP1.
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