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Catalog No: OAAB12896
Size:400UL
Price: $396.00
SKU
OAAB12896
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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Datasheets/ManualsPrintable datasheet for SPIRE1 Antibody (C-term) (OAAB12896)
Product Info
Predicted Species ReactivityHuman, Mouse, Primate
Product FormatLiquid.PBS with 0.09% (W/V) sodium azide
ClonalityPolyclonal
IsotypeIg
HostRabbit
ApplicationWestern blot
Additional InformationCellular Location: Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Detected at the cleavage furrow during asymmetric oocyte division and polar body extrusion. Punctate spots in perinuclear region and cytoplasm, colocalized with Rab11.
Reconstitution and StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis SPIRE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-691 amino acids from the C-terminal region of human SPIRE1.
PurificationThis antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration0.34 mg/ml
Application InfoWB: 1:1000
Optimal dilutions should be determined by the end user.
ReferenceRose, J. Phd, et al. Mol. Med. (2010) In press
Pechlivanis, M., et al. J. Biol. Chem. 284(37):25324-25333(2009)
Bosch, M., et al. Mol. Cell 28(4):555-568(2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007)
Kerkhoff, E., et al. Curr. Biol. 11(24):1963-1968(2001)
Publications

Correction: DNA damage induces nuclear actin filament assembly by Formin-2 and Spire-1/2 that promotes efficient DNA repair. Elife. 4, (2015). 26437453

DNA damage induces nuclear actin filament assembly by Formin -2 and Spire-½ that promotes efficient DNA repair. [corrected]. Elife. 4, e07735 (2015). 26287480

Description
Gene SymbolSPIRE1
Gene Full Namespire type actin nucleation factor 1
Alias Symbolsprotein spire homolog 1;Spir-1;spire actin nucleation factor 1;spire family actin nucleation factor 1;spire homolog 1.
NCBI Gene Id56907
Protein NameNP_001122098.1, NP_001122099.1, NP_064533.3, Q08AE8, Q4R707, Q52KF3
Description of TargetProtein spire homolog 1, protein spire homolog 1 isoform a [Homo sapiens], protein spire homolog 1 isoform b [Homo sapiens], protein spire homolog 1 isoform c [Homo sapiens]
Uniprot IDhttps://www.uniprot.org/uniprot/?query=Q08AE8+OR+Q4R707+OR+Q52KF3
Protein Accession #https://www.ncbi.nlm.nih.gov/protein/NP_001122098.1,NP_001122099.1,NP_064533.3
Molecular Weight85544
  1. What is the species homology for "SPIRE1 Antibody - C-terminal region (OAAB12896)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Primate".

  2. How long will it take to receive "SPIRE1 Antibody - C-terminal region (OAAB12896)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks ".

  3. What buffer format is "SPIRE1 Antibody - C-terminal region (OAAB12896)" provided in?

    This item is provided in "Liquid.PBS with 0.09% (W/V) sodium azide".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "SPIRE1 Antibody - C-terminal region (OAAB12896)"?

    This target may also be called "protein spire homolog 1;Spir-1;spire actin nucleation factor 1;spire family actin nucleation factor 1;spire homolog 1." in publications.

  5. What is the shipping cost for "SPIRE1 Antibody - C-terminal region (OAAB12896)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "SPIRE1 Antibody - C-terminal region (OAAB12896)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "SPIRE1 Antibody - C-terminal region (OAAB12896)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "85544".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "SPIRE1 Antibody - C-terminal region (OAAB12896)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "SPIRE1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "SPIRE1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "SPIRE1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "SPIRE1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "SPIRE1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "SPIRE1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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