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SPHK1 Antibody - N-terminal region (OASA08181)

50 ug
$770.00
In Stock
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Gene Symbol:
SPHK1
NCBI Gene Id:
8877
Protein Name:
Sphingosine kinase 1
Swissprot Id:
Q9NYA1
Protein Accession #:
NP_001136073.1
Alias Symbols:
SPHK, SPHK1
Replacement Item:
This antibody may replace item sc-100441 from Santa Cruz Biotechnology.
Description of Target:
RABBIT ANTI HUMAN SPHK1 (N-TERMINAL)
Protein Size (# AA):
384
Host:
Rabbit
Clonality:
Polyclonal
Application:
IHC-FFPE
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express SPHK1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express SPHK1.
Immunogen:
The immunogen for anti-SPHK1 antibody: synthetic peptide: N-terminal domain of human SphK1, conjugated to KLH.
Predicted Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Human
Product Format:
Purified IgG - liquid
Reconstitution and Storage:
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Datasheets/Manuals:
Printable datasheet for anti-SPHK1 antibody - OASA08181
Specificity:
SPHK1
Isotype:
Polyclonal IgG
Application Info:
Immunohistology - Paraffin(1):    5 - 15ug/ml
(1)Special conditions apply. See (*).
Additional Information:
Histology Positive Control Tissue: Adrenal, Pheochromocytes.
:::
Preservative Stabilisers: 0.01% - Sodium Azide (NaN3)
Antiserum Preparation: Antisera to SphK1 were raised by repeated immunisations of rabbit with highly purified antigen. Purified IgG prepared by affinity chromatography.
:::
Approx Protein Conc: IgG concentration 1.0mg/ml
Buffer Solutions: Phosphate buffered saline pH7.7
Target Reference:
1. Maceyka, M. et al. (2005) SphK1 and SphK2, Sphingosine Kinase Isoenzymes with Opposing Functions in Sphingolipid Metabolism. J. Biol. Chem. 280: 37118 - 37129.
2. Alemany, R. et al. (2007) Regulation and functional roles of sphingosine kinases. Naunyn Schmiedebergs Arch. Pharmacol. 374: 413-428.

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