SP100 Antibody - N-terminal region (OAAB11085)

Catalog No: OAAB11085

Size:400ul

SP100 Antibody (N-term) (Cat. #OAAB11085) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the SP100 antibody detected the SP100 protein (arrow).

There is BioGPS gene expression data showing that SP100 is expressed in ZR75-1

Product Info

• Predicted Species Reactivity: Human
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB
• Additional Information: Precautions: SP100 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: May play a role in the control of gene expression.
  Cellular Location: Nucleus, PML body. Note=Found in the nuclear body, also known as nuclear domain 10 (ND10), PML oncogenic domain (POD), nuclear dots (ND) and KR body. The nuclear body is a nucleoplasmic structure of punctate shape, which varies in size and number. Induction by interferon and may be cell cycle stages modulate the subnuclear localization of the isoforms
  Tissue Location: Widely expressed. Sp100-B is expressed only in spleen, tonsil, thymus, mature B-cell line and some T-cell line, but not in brain, liver, muscle or non-lymphoid cell lines
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This SP100 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-227 amino acids from the N-terminal region of human SP100.
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Sample Type Confirmation:

  There is BioGPS gene expression data showing that SP100 is expressed in ZR75-1

• Application Info: WB: 1:1000

Target Info

• Gene Symbol: SP100
• Alias Symbols: lysp100b
• NCBI Gene Id: 6672
• Protein Name: Nuclear autoantigen Sp-100
• Description of Target: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: P23497
• Protein Accession #: NP_001073860.1
• Molecular Weight: 100417 Da