SP1 Antibody (OASG06763)

Catalog No: OASG06763

Size:100 uL

Western Blot using A549

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC, IF
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human Sp1 around the non-phosphorylation site of T739. Location: 680-760aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: Sp1 Polyclonal Antibody detects endogenous levels of Sp1 protein.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000;

Target Info

• Gene Symbol: SP1
• Gene Full Name: Sp1 transcription factor
• Alias Symbols: SP1, TSFP1, Transcription factor Sp1
• NCBI Gene Id: 6667; 20683; 24790
• Description of Target: The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.
• Uniprot ID: P08047, O89090, Q01714
• Molecular Weight: 85 kDa