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SP1 Antibody - middle region (ARP43585_P050)

100 ul
$289.00
In Stock
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Conjugation Options

ARP43585_P050-FITC Conjugated

ARP43585_P050-HRP Conjugated

ARP43585_P050-Biotin Conjugated

Tested Species Reactivity:
Human
Predicted Species Reactivity:
Cow, Dog, Goat, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality:
Polyclonal
Host:
Rabbit
Conjugation:
Unconjugated
Application:
WB
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Gene Symbol:
SP1
Official Gene Full Name:
Sp1 transcription factor
NCBI Gene Id:
6667
Protein Name:
Transcription factor Sp1
Swissprot Id:
P08047
Protein Accession #:
NP_612482
Nucleotide Accession #:
NM_138473
Alias Symbols:
-
Replacement Item:
This antibody may replace item sc-14027 from Santa Cruz Biotechnology.
Description of Target:
SP1 belongs to the Sp1 C2H2-type zinc-finger protein family. It contains 3 C2H2-type zinc fingers. SP1 binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. It can interact with G/C-rich motifs from serotonin receptor promoter.
Protein Size (# AA):
785
Molecular Weight:
81kDa
Purification:
Affinity Purified
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express SP1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express SP1.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human SP1
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 87%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Complete computational species homology data:
Anti-SP1 (ARP43585_P050)
Peptide Sequence:
Synthetic peptide located within the following region: TLTPIASAASIPAGTVTVNAAQLSSMPGLQTINLSALGTSGIQVHPIQGL
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
JUN; UBC; HIC1; HDAC1; SP3; TP53; CTNNB1; ARHGAP21; SENP6; C3orf17; USP39; FOXM1; ESR1; DDX5; KIF1A; PPIG; TPI1; TFAP2A; NAP1L1; HDAC2; NUP62; MYC; HIF1A; POU2F1; SMAD3; DDX3X; TBP; SP1; RBL1; Taf4; tat; ESR2; VHL; YY1; CASP7; CASP6; CASP3; HTT; BRCA1; MA
Blocking Peptide:
For anti-SP1 (ARP43585_P050) antibody is Catalog # AAP43585 (Previous Catalog # AAPS13612)
Datasheets/Manuals:
Printable datasheet for anti-SP1 (ARP43585_P050) antibody
Target Reference:
Yoshimura,M., (2008) Biochem. Biophys. Res. Commun. 369 (3), 939-942

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