SOX4 Antibody - N-terminal region (OABB02101)

Catalog No: OABB02101

Size:100UG

Anti-SOX4 Picoband antibody, OABB02101, Western blotting
All lanes: Anti SOX4 (OABB02101) at 0.5ug/ml
Lane 1: MCF-7 Whole Cell Lysate at 40ug
Lane 2: 293T Whole Cell Lysate at 40ug
Predicted bind size: 47KD
Observed bind size: 47KD

Product Info

• Tested Species Reactivity: Human, Mouse
• Predicted Species Reactivity: Hamster|Human|Mouse
• Product Format: Lyophilized. Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Clonality: Polyclonal
• Clone: Polyclonal
• Isotype: Rabbit IgG
• Host: Rabbit
• Application: Western blot
• Additional Information: Notes: Tested Species: In-house tested species with positive results.
  Other applications have not been tested.
  Optimal dilutions should be determined by end users.
  Background: Transcription factor SOX-4 is a protein that in humans is encoded by the SOX4 gene. This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). This protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.
• Reconstitution and Storage: 2°C to 8°C|-20°C
• Immunogen: Polypeptide
• Purification: Affinity Purified
• Peptide Sequence: Synthetic peptide located within the following region: MVQQTNNAENTEALLAGESSDSGAGLELGIA
• Concentration: 500 ug/ml
• Specificity: No cross reactivity with other proteins.
• Application Info: Western blot: 0.1-0.5 ug/ml: Human, Mouse
• Reference: 1. "Entrez Gene: SOX4 SRY (sex determining region Y)-box 4".
  2. Critcher R, Stitson RN, Wade-Martins R, Easty DJ, Farr CJ (October 1998). "Assignment of Sox4 to mouse chromosome 13 bands A3-A5 by fluorescence in situ hybridization; refinement of the human SOX4 location to 6p22.3 and of SOX20 to chromosome 17p12.3". Cytogenet Cell Genet81 (3–4): 294–5.
  3. Farr CJ, Easty DJ, Ragoussis J, Collignon J, Lovell-Badge R, Goodfellow PN (January 1994). "Characterization and mapping of the human SOX4 gene". Mamm Genome 4 (10): 577–84.
  
• Storage Buffer: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Description: Rabbit IgG polyclonal antibody for Transcription factor SOX-4(SOX4) detection. Tested with WB in Human;Mouse.

Target Info

• Gene Symbol: SOX4
• Gene Full Name: SRY-box transcription factor 4
• Alias Symbols: CSS10;ecotropic viral integration site 16;EVI16;SRY (sex determining region Y)-box 4;SRY-box 4;SRY-related HMG-box gene 4;transcription factor SOX-4.
• NCBI Gene Id: 6659
• Protein Name: Transcription factor SOX-4
• Description of Target: Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif.
• Uniprot ID: Q06945
• Molecular Weight: 47263 MW