Catalog No: OAAB22145
Size:100ul
Price: $450.00
SKU
OAAB22145
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for anti-SOX2 (OAAB22145) antibody
Product Info
Predicted Species ReactivityHuman, Mouse
Product FormatLiquid
ClonalityMonoclonal
HostRabbit
ApplicationWB, ICC, FC
Additional InformationFunction: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Predicted Homology Based on Immunogen SequenceHuman, Mouse
Preservative0.02% Sodium Azide and 50% glycerol
FormulationPurified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol
Application InfoWB: 1:1000
ICC: 1:150
FC: 1:100
ReferenceStevanovic M.,et al.Mamm. Genome 5:640-642(1994).
Sadler L.A.,et al.Submitted (DEC-1992) to the EMBL/GenBank/DDBJ databases.
Fantes J.,et al.Nat. Genet. 33:461-463(2003).
Takahashi K.,et al.Cell 131:861-872(2007).
Rigbolt K.T.,et al.Sci. Signal. 4:RS3-RS3(2011).
Gene SymbolSOX2
Gene Full NameSRY-box 2
Alias SymbolsANOP3, MCOPS3
NCBI Gene Id6657
Description of TargetThis intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
Uniprot IDP48431
Protein Accession #NP_003097.1
Nucleotide Accession #NM_003106.3
Molecular Weight34 kDa
  1. What is the species homology for "SOX2 Antibody (OAAB22145)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".

  2. How long will it take to receive "SOX2 Antibody (OAAB22145)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "SOX2 Antibody (OAAB22145)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "SOX2 Antibody (OAAB22145)"?

    This target may also be called "ANOP3, MCOPS3" in publications.

  5. What is the shipping cost for "SOX2 Antibody (OAAB22145)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "SOX2 Antibody (OAAB22145)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "SOX2 Antibody (OAAB22145)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "34 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "SOX2 Antibody (OAAB22145)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "SOX2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "SOX2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "SOX2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "SOX2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "SOX2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "SOX2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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