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Datasheets/Manuals | Printable datasheet for anti-SORL1 (OAEC04352) antibody |
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Predicted Species Reactivity | Human |
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Product Format | Ascitic fluid containing 0.03% sodium azide |
Clonality | Monoclonal |
Clone | 3B6B11 |
Isotype | IgG1 |
Host | Mouse |
Reconstitution and Storage | Store at 4C, for long term storage, store at -20C. |
Immunogen | Purified recombinant fragment of human SORL1 expressed in EColi. |
Concentration | 1 mg/ml |
Application Info | WB: 1/500 - 1/2000 IHC: 1/200 - 1/1000 IF: 1/200 - 1/1000 ELISA: 1/10000 |
Gene Symbol | SORL1 |
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Gene Full Name | sortilin-related receptor, L(DLR class) A repeats containing |
Alias Symbols | LR11, LRP9, SORLA, gp250, SorLA-1, C11orf32 |
NCBI Gene Id | 6653 |
Description of Target | SORL1 (sortilin-related receptor, L A repeats containing) also known as sorting protein-related receptor containing LDLR class A (SorLA), is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP (receptor-associated protein). SorLA is a multifunctional endocytis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous SorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. The gene encoding for the protein maps to chromosome 8p23.1. SorLA is expressed mainly in brain. |
Uniprot ID | Q92673 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "SORL1 Antibody (OAEC04352)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "SORL1 Antibody (OAEC04352)"?
This item is available "Domestic: within 2-3 weeks delivery | International: 2-3 weeks".
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What buffer format is "SORL1 Antibody (OAEC04352)" provided in?
This item is provided in "Ascitic fluid containing 0.03% sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "SORL1 Antibody (OAEC04352)"?
This target may also be called "LR11, LRP9, SORLA, gp250, SorLA-1, C11orf32" in publications.
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What is the shipping cost for "SORL1 Antibody (OAEC04352)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "SORL1 Antibody (OAEC04352)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "SORL1 Antibody (OAEC04352)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "SORL1 Antibody (OAEC04352)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "SORL1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "SORL1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "SORL1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "SORL1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "SORL1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "SORL1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.