SOD2 Antibody (OAED00131)

Catalog No: OAED00131

Size:50 ug

Western blot analysis of Mn SOD: Lane 1: MW Marker; Lane 2: HeLa Cell Lysate; Lane 3: Mouse Brain Tissue Extract; Lane 4: Rat Brain Tissue Extract

Immunohistochemistry analysis of human skeletal muscle tissue stained with Mn SOD, pAb at 10 ug/ml.

Product Info

• Predicted Species Reactivity: Bovine|Dog|Guinea Pig|Hamster|Human|Monkey|Mouse|Rabbit|Rat|Sheep|Xenopus
• Clonality: Polyclonal
• Host: Rabbit
• Application: Immunohistochemistry|Western blot
• Reconstitution and Storage: Long Term Storage : -20C
  
• Immunogen: Human Mn SOD protein.
• Specificity: Recognizes human, mouse, rat, bovine, dog, guinea pig, hamster, monkey, pig, rabbit, sheep and Xenopus Mn SOD. Detects a band of ~25kDa by Western blot.
• Formulation: Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
• Purity: Protein A affinity purified.
  
• Application Info: Immunohistochemistry
  Western Blot (1:1000, colorimetric)
  Optimal conditions must be determined individually for each application.
• Reference: Glutathione depletion in antioxidant defense of differentiated NT2-LHON cybrids: E. Kirches, et al. ; Neurobiol. Dis. 25, 536 (2007), Application(s): WB using human cell lysates, Abstract;
  The role of peroxisomal ABC transporters in the mouse adrenal gland:the loss of Abcd2 (ALDR), Not Abcd1 (ALD), causes oxidative damage: J. Powers, et al. ; Lab. Invest. 87, 261 (2007), Application(s): IHC using mouse tissue, Abstract;
  TLR4-mediated survival of macrophages is MyD88 dependent and requires TNF-alpha autocrine signalling: E. Lombardo, et al. ; J. Immunol. 178, 3731 (2007), Application(s): WB using mouse cell lysates, Abstract;
  Time sequence of maturation of dystrophic neurites associated with Abeta deposits in APP/PS1 transgenic mice: L. Pradier, et al. ; Exp. Neurol. 184, 247 (2003), Application(s): IHC using mouse samples, Abstract;
  Heme oxygenase-1-derived carbon monoxide requires the activation of transcription factor NF-kappa B to protect endothelial cells from tumor necrosis factor-alpha -mediated apoptosis: M.P. Soares, et al. ; J. Biol. Chem. 277, 17950 (2002), Application(s): WB using human & bovine samples, Abstract;
  

Target Info

• Gene Symbol: SOD2
• Gene Full Name: superoxide dismutase 2
• Alias Symbols: epididymis secretory sperm binding protein;gastric cancer-associated lncRNA 1;GClnc1;indophenoloxidase B;IPOB;IPO-B;manganese-containing superoxide dismutase;mangano-superoxide dismutase;Mn superoxide dismutase;Mn-SOD;MNSOD;MVCD6;superoxide dismutase [Mn], mitochondrial;superoxide dismutase 2, mitochondrial.
• NCBI Gene Id: 6648
• Protein Name: Superoxide dismutase [Mn], mitochondrial
• Description of Target: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
• Uniprot ID: P04179
• Protein Accession #: NP_000627.2; NP_001019636.1; NP_001019637.1
• Nucleotide Accession #: NM_000636.2; NM_001024465.1; NM_001024466.1