Size:100 ul
Special Price $229.00 Regular Price $319.00
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ARP42148_P050
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Conjugation Options

ARP42148_P050-FITC Conjugated

ARP42148_P050-HRP Conjugated

ARP42148_P050-Biotin Conjugated

SOCS1 Antibody - middle region (ARP42148_P050)

Rating:
100% of 100
Catalog#: ARP42148_P050
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human, Rat
Predicted Species Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-7006 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human SOCS1
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Complete computational species homology data Anti-SOCS1 (ARP42148_P050)
Peptide Sequence Synthetic peptide located within the following region: RQRNCFFALSVKMASGPTSIRVHFQAGRFHLDGSRESFDCLFELLEHYVA
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-SOCS1 (ARP42148_P050) antibody is Catalog # AAP42148 (Previous Catalog # AAPS11809)
Datasheets/Manuals Printable datasheet for anti-SOCS1 (ARP42148_P050) antibody
Gene Symbol SOCS1
Official Gene Full Name Suppressor of cytokine signaling 1
Alias Symbols CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3
NCBI Gene Id 8651
Protein Name Suppressor of cytokine signaling 1
Description of Target SOCS1 is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. SOCS1 functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of its gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
Swissprot Id O15524
Protein Accession # NP_003736
Nucleotide Accession # NM_003745
Protein Size (# AA) 211
Molecular Weight 23kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express SOCS1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express SOCS1.
Protein Interactions CSF2RB; TCEB1; ERBB2; ABL1; CYTIP; gag; TP53; JAK2; ATR; ATM; JAK1; INSR; FGFR3; LCK; RASA1; PDCD1; IRS1; ETV6; DAB1; TIRAP; VHL; VAV1; TUBG1; RELA; MAP3K5; CLEC7A; PTPN11; TYK2; IRF3; IFNAR1; TCEB2; ALK; COMMD1; TRIM8; PIK3R2; GHR; IRS2; TEC; NCK1; VAV2;
  1. What is the species homology for "SOCS1 Antibody - middle region (ARP42148_P050)"?

    The tested species reactivity for this item is "Human, Rat". This antibody is predicted to have homology to "Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat".

  2. How long will it take to receive "SOCS1 Antibody - middle region (ARP42148_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "SOCS1 Antibody - middle region (ARP42148_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "SOCS1 Antibody - middle region (ARP42148_P050)"?

    This target may also be called "CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3" in publications.

  5. What is the shipping cost for "SOCS1 Antibody - middle region (ARP42148_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "SOCS1 Antibody - middle region (ARP42148_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "SOCS1 Antibody - middle region (ARP42148_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "23kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "SOCS1 Antibody - middle region (ARP42148_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "SOCS1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "SOCS1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "SOCS1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "SOCS1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "SOCS1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "SOCS1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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