SNAP25 Antibody (OAEG00219)

Catalog No: OAEG00219

Size:100ug

SNAP25 (Synaptosome-Associated Protein of 25 kDa) is a membrane bound, pre-synaptic nerve terminal protein that plays an essential role in synaptic vesicle fusion and exocytosis. It is involved in the molecular regulation of neurotransmitter release. It is thought to play an important role in the synaptic function of specific neuronal systems. SNAP25 associates with proteins involved in vesicle docking and membrane fusion. SNAP25 exists as two alternatively spliced isoforms, SNAP25A and SNAP25B. These isoforms are differentially expressed in neurons and neuroendocrine cells. These two isoforms differ by 9 amino acids in the central portion of the protein.

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Monkey, Chicken, Cow
• Product Format: Liquid PBS with 0.08% sodium azide
• Clonality: Monoclonal
• Clone: S-7B8
• Isotype: IgG1
• Host: Mouse
• Application: WB, IHC
• Reconstitution and Storage: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
• Immunogen: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with rat brain synaptosomal membranes and mouse NS1 cells.
• Purification: Protein A/G Chromatography
• Concentration: Varies by lot. See vial for concentration.
• Source: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with rat brain synaptosomal membranes and mouse NS1 cells.
• Application Info: Antibody can be used for Western blotting (1-5 ug/ml), immunocytochemistry and immunohistochemistry on paraformaldehyde fixed CNS tissues (1-5 ug/ml). Does not stain reduced proteins.

Target Info

• Gene Symbol: SNAP25