Catalog No: OPCA03615 (Formerly GWB-IGEEI0)
Price: $0.00
SKU
OPCA03615
Bulk
Order
Aviva's
Satisfaction
Guarantee
Contact Us:
Shipping Info:
  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.

Snaclec rhodocytin subunit alpha Recombinant Protein (Malayan pit viper) (OPCA03615)

Product Info
Predicted Species ReactivityCalloselasma rhodostoma
Product FormatLiquid or Lyophilized powder
::Relevance: Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the Cytoplasmic domain tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial.
Reconstitution and Storage-20°C or -80°C
PurificationAffinity purified using IMAC
Concentration0.1-5 mg/ml (Bradford method)
PurityGreater than 90% as determined by SDS-PAGE.
Peptide SequenceGLEDCDFGWSPYDQHCYQAFNEQKTWDEAEKFCRAQENGAHLASIESNGEADFVSWLISQKDELADEDYVWIGLRAQNKEQQCSSEWSDGSSVSYENLIDLHTKKCGALEKLTGFRKWVNYYCEQMHAFVCKLLPY
Protein SequenceGLEDCDFGWSPYDQHCYQAFNEQKTWDEAEKFCRAQENGAHLASIESNGEADFVSWLISQKDELADEDYVWIGLRAQNKEQQCSSEWSDGSSVSYENLIDLHTKKCGALEKLTGFRKWVNYYCEQMHAFVCKLLPY
Storage BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
SourceYeast
Protein Range1-136 aa
TagN-terminal 6xHis-tagged
ReferenceMolecular cloning and sequence analysis of aggretin, a collagen-like platelet aggregation inducer.Chung C.-H., Au L.-C., Huang T.-F.Biochem. Biophys. Res. Commun. 263:723-727(1999)
Alias SymbolsAggretin alpha chain;Rhodoaggretin subunit alpha.
Protein NameSnaclec rhodocytin subunit alpha
Description of TargetElicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial.
Uniprot IDQ9I841
Protein Size (# AA)Recombinant
Molecular Weight17.8 kDa
Write Your Own Review
You're reviewing:Snaclec rhodocytin subunit alpha Recombinant Protein (Malayan pit viper) (OPCA03615)
Your Rating