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| Datasheets/Manuals | Printable datasheet for SMYD3 Antibody (OACA07249) (OACA07249) |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot |
| Reconstitution and Storage | -20°C or -80°C |
| Immunogen | Recombinant Human Histone-lysine N-methyltransferase SMYD3 protein (199-428AA) |
| Purification | Affinity Purified |
| Preservative | 0.02% sodium azide |
| Formulation | PBS with, 50% glycerol, pH7.3. |
| Reference | [1]"Crystal structure of human histone-lysine n-methyltransferase SMYD3 in complex with S-adenosyl-L-methionine."Structural genomics consortium (SGC)Submitted (APR-2010). [3]"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012). [3]"Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation."Van Aller G.S., Reynoird N., Barbash O., Huddleston M., Liu S., Zmoos A.F., McDevitt P., Sinnamon R., Le B., Mas G., Annan R., Sage J., Garcia B.A., Tummino P.J., Gozani O., Kruger R.G.Epigenetics 7:340-343(2012). |
| Gene Symbol | SMYD3 |
|---|---|
| Gene Full Name | SET and MYND domain containing 3 |
| Alias Symbols | bA74P14.1;histone-lysine N-methyltransferase SMYD3;KMT3E;SET and MYND domain-containing protein 3;zinc finger MYND domain-containing protein 1;zinc finger protein, subfamily 3A (MYND domain containing), 1;zinc finger, MYND domain containing 1;ZMYND1;ZNFN3A1. |
| NCBI Gene Id | 64754 |
| Protein Name | Histone-lysine N-methyltransferase SMYD3 |
| Description of Target | Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di- and tri-methylation, but not monomethylation (PubMed:15235609, PubMed:22419068). Also methylates 'Lys-5' of histone H4 (PubMed:22419068). Plays an important role in transcriptional activation as a member of an RNA polymerase complex (PubMed:15235609). Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences (PubMed:15235609). |
| Uniprot ID | Q9H7B4 |
| Protein Accession # | NP_001161212 |
| Nucleotide Accession # | NM_001167740 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "SMYD3 Antibody (OACA07249)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "SMYD3 Antibody (OACA07249)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "SMYD3 Antibody (OACA07249)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "SMYD3 Antibody (OACA07249)"?
This target may also be called "bA74P14.1;histone-lysine N-methyltransferase SMYD3;KMT3E;SET and MYND domain-containing protein 3;zinc finger MYND domain-containing protein 1;zinc finger protein, subfamily 3A (MYND domain containing), 1;zinc finger, MYND domain containing 1;ZMYND1;ZNFN3A1." in publications.
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What is the shipping cost for "SMYD3 Antibody (OACA07249)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "SMYD3 Antibody (OACA07249)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "SMYD3 Antibody (OACA07249)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "SMYD3 Antibody (OACA07249)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "SMYD3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "SMYD3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "SMYD3"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "SMYD3"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "SMYD3"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "SMYD3"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
