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SKU
OACD07385
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More Information
Predicted Species Reactivity Human
Product Format Liquid
Clonality Polyclonal
Isotype IgG
Host Rabbit
Application WB, ICC, IHC-P, IHC-F
Reconstitution and Storage Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
Immunogen Range: Ser994 - Glu1181
Purification Antigen-specific affinity chromatography
Concentration 500ug/mL
Datasheets/Manuals Printable datasheet for anti-SMC3 (OACD07385) antibody
Preservative 0.02% NaN3
Specificity The antibody is a rabbit polyclonal antibody raised against SMC3. It has been selected for its ability to recognize SMC3 in immunohistochemical staining and western blotting.
Formulation PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Application Data Western blotting: 1:50-400
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-1:5,000
Optimal working dilutions must be determined by end user.
Gene Symbol SMC3
Official Gene Full Name Structural maintenance of chromosomes 3
Alias Symbols BAM, bamacan, Bamacan, Basement membrane-associated chondroitin proteoglycan, BMH, CDLS3, Chondroitin sulfate proteoglycan 6, Chromosome-associated polypeptide, CSPG6, hCAP, HCAP, SMC-3, SMC3L1, SMC protein 3, Structural maintenance of chromosomes protein
NCBI Gene Id 9126
Protein Name Structural maintenance of chromosomes protein 3
Description of Target Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement.
Swissprot Id Q9UQE7
Protein Accession # NP_005436.1
Nucleotide Accession # NM_005445
Molecular Weight 142 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express SMC3.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express SMC3.
  1. What is the species homology for "SMC3 Antibody (OACD07385)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "SMC3 Antibody (OACD07385)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "SMC3 Antibody (OACD07385)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "SMC3 Antibody (OACD07385)"?

    This target may also be called "BAM, bamacan, Bamacan, Basement membrane-associated chondroitin proteoglycan, BMH, CDLS3, Chondroitin sulfate proteoglycan 6, Chromosome-associated polypeptide, CSPG6, hCAP, HCAP, SMC-3, SMC3L1, SMC protein 3, Structural maintenance of chromosomes protein" in publications.

  5. What is the shipping cost for "SMC3 Antibody (OACD07385)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "SMC3 Antibody (OACD07385)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "SMC3 Antibody (OACD07385)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "142 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "SMC3 Antibody (OACD07385)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "SMC3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "SMC3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "SMC3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "SMC3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "SMC3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "SMC3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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