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Catalog No: ATP00013_T100
Size:100ul
Price: $339.00
SKU
ATP00013_T100
Availability: Domestic: within 24 hours delivery International: 3-5 business days
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.
Datasheets/ManualsPrintable datasheet for SMC1A Polyclonal Antibody (Human) (ATP00013)
Product Info
Predicted Species ReactivityHuman
Product FormatPBS w/ 0.09% sodium azide
ClonalityPolyclonal
IsotypeIgG
ApplicationWB;ICC
Reconstitution and StorageStore at -20C
ImmunogenRecombinant Human SMC1A aa 489-667
PurificationProtein A
Concentration1 mg/mL
Gene SymbolStructural maintenance of chromosomes protein 1A
Gene Full NameSMC1A
Alias SymbolsSMC1A
NCBI Gene Id8243
Description of TargetInvolved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint.
Uniprot ID Q14683
Protein Accession #Q14683
Molecular Weight143 kDa (1233 aa)
  1. What is the species homology for "SMC1A Polyclonal Antibody (Human) (ATP00013_T100)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "SMC1A Polyclonal Antibody (Human) (ATP00013_T100)"?

    This item is available "Domestic: within 24 hours delivery International: 3-5 business days".

  3. What buffer format is "SMC1A Polyclonal Antibody (Human) (ATP00013_T100)" provided in?

    This item is provided in "PBS w/ 0.09% sodium azide".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "SMC1A Polyclonal Antibody (Human) (ATP00013_T100)"?

    This target may also be called "SMC1A" in publications.

  5. What is the shipping cost for "SMC1A Polyclonal Antibody (Human) (ATP00013_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "SMC1A Polyclonal Antibody (Human) (ATP00013_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "SMC1A Polyclonal Antibody (Human) (ATP00013_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "143 kDa (1233 aa)".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "SMC1A Polyclonal Antibody (Human) (ATP00013_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "SMC1A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "SMC1A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "SMC1A"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "SMC1A"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "SMC1A"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "SMC1A"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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