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SMARCB1 antibody - N-terminal region (ARP34171_P050)

100 ul
$319.00
In Stock

Conjugation Options

ARP34171_P050-FITC Conjugated

ARP34171_P050-HRP Conjugated

ARP34171_P050-Biotin Conjugated

Gene Symbol:
SMARCB1
NCBI Gene Id:
6598
Official Gene Full Name:
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Protein Name:
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
Swissprot Id:
Q12824
Protein Accession #:
NP_003064
Nucleotide Accession #:
NM_003073
Alias Symbols:
RDT, INI1, SNF5, Snr1, BAF47, RTPS1, Sfh1p, hSNFS, SNF5L1
Replacement Item:
This antibody may replace item sc-13055 from Santa Cruz Biotechnology.
Description of Target:
The protein encoded by SMARCB1 is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. SMARCB1 has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors.
Protein Size (# AA):
385
Molecular Weight:
44kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express SMARCB1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express SMARCB1.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human SMARCB1
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%
Complete computational species homology data:
Anti-SMARCB1 (ARP34171_P050)
Peptide Sequence:
Synthetic peptide located within the following region: RGSLYKRYPSLWRRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVT
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; SOX2; tat; EPAS1; TRA2A; NCSTN; SAP18; EIF4A3; ARID1A; DPF1; VTN; TOP2B; SON; SMARCE1; SMARCD3; SMARCD2; SMARCD1; SMARCC2; SMARCA4; SMARCA2; SMARCC1; ARID1B; HDAC2; APP; PHF10; UBD; COPS5; CUL3; TFAP4; CAND1; RB1CC1; UBB; CEBPB; UL114; UL44; CHFR; DP
Blocking Peptide:
For anti-SMARCB1 (ARP34171_P050) antibody is Catalog # AAPP05433
Datasheets/Manuals:
Printable datasheet for anti-SMARCB1 (ARP34171_P050) antibody
Target Reference:
Mueller,W., et al., (2004) Neuropathol Appl Neurobiol 30 (3), 304-307

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