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SMARCB1 Antibody - middle region (ARP34172_P050)

100 ul
$289.00
In Stock
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Conjugation Options

ARP34172_P050-FITC Conjugated

ARP34172_P050-HRP Conjugated

ARP34172_P050-Biotin Conjugated

Gene Symbol:
SMARCB1
Official Gene Full Name:
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
NCBI Gene Id:
6598
Protein Name:
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
Swissprot Id:
Q12824-2
Protein Accession #:
NP_001007469
Nucleotide Accession #:
NM_001007468.2
Alias Symbols:
RDT, CSS3, INI1, SNF5, Snr1, BAF47, MRD15, RTPS1, Sfh1p, hSNFS, SNF5L1, SWNTS1, PPP1R144
Replacement Item:
This antibody may replace item sc-13055 from Santa Cruz Biotechnology.
Description of Target:
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene.
Protein Size (# AA):
376
Molecular Weight:
41 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express SMARCB1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express SMARCB1.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human SMARCB1
Predicted Species Reactivity:
Human
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
Complete computational species homology data:
Anti-SMARCB1 (ARP34172_P050)
Peptide Sequence:
Synthetic peptide located within the following region: PLTFVPAIASAIRQQIESYPTDSILEDQSDQRVIIKLNIHVGNISLVDQF
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; SOX2; tat; EPAS1; TRA2A; NCSTN; SAP18; EIF4A3; ARID1A; DPF1; VTN; TOP2B; SON; SMARCE1; SMARCD3; SMARCD2; SMARCD1; SMARCC2; SMARCA4; SMARCA2; SMARCC1; ARID1B; HDAC2; APP; PHF10; UBD; COPS5; CUL3; TFAP4; CAND1; RB1CC1; UBB; CEBPB; UL114; UL44; CHFR; DP
Blocking Peptide:
For anti-SMARCB1 (ARP34172_P050) antibody is Catalog # AAP34172
Datasheets/Manuals:
Printable datasheet for anti-SMARCB1 (ARP34172_P050) antibody
Sample Type Confirmation:

SMARCB1 is supported by BioGPS gene expression data to be expressed in Jurkat

Conjugation:
Unconjugated
Target Reference:
Kimura,K., et al., (2006) Genome Res. 16 (1), 55-65

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