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SMARCA2 Antibody (OACA02435)

Catalog#: OACA02435
Domestic: within 1-2 weeks delivery | International: 1-2 weeks
More Information
Predicted Species ReactivityHuman
Product FormatLiquid
ApplicationIHC, CHIP
Reconstitution and StorageStore at 4C for up to one month. For long term storage, aliquot and store at -20C or -80C. Avoid freeze thaw cycles.
Replacement ItemThis antibody may replace item sc-135850 from Santa Cruz Biotechnology.
ImmunogenRecombinant human Probable global transcription activator SNF2L2 protein (700-1216aa)
PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
Predicted Homology Based on Immunogen SequenceHuman
Datasheets/ManualsPrintable datasheet for anti-SNF2L2 (OACA02435) antibody
FormulationProvided in PBS, pH 7.4, 50% Glycerol, 0.03% Proclin 300
Target Reference[1] A quantitative atlas of mitotic phosphorylation. Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767 (2008).
[2] Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography. Han G., Ye M., Zhou H., Jiang X., Feng S., Jiang X., Tian R., Wan D., Zou H., Gu J. Proteomics 8:1346-1361 (2008).
[3] Initial characterization of the human central proteome. Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17 (2011).
Gene SymbolSMARCA2
Official Gene Full NameSWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Alias SymbolsBRM, SNF2, SWI2, hBRM, NCBRS, Sth1p, BAF190, SNF2L2, SNF2LA, hSNF2a
NCBI Gene Id6595
Protein Nameprobable global transcription activator SNF2L2
Description of TargetThe protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.
Swissprot IdP51531
Protein Accession #NP_001276325.1
Nucleotide Accession #NM_001289396.1
Protein Size (# AA)1590
Molecular Weight181 kDa
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express SMARCA2.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express SMARCA2.
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