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SMAD3 Antibody (Phospho-Ser208) (OASG06703)

100 uL
$215.00
In Stock
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Gene Symbol:
SMAD3
Official Gene Full Name:
SMAD family member 3
NCBI Gene Id:
4088; 17127; 25631
Swissprot Id:
P84022, Q8BUN5, P84025
Alias Symbols:
SMAD3, MADH3, Mothers against decapentaplegic homolog 3, MAD homolog 3, Mad3, Mothers against DPP homolog 3, hMAD-3, JV15-2, SMAD family member 3, SMAD 3, Smad3, hSMAD3
Replacement Item:
This antibody may replace item sc-101154 from Santa Cruz Biotechnology.
Description of Target:
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
Molecular Weight:
40 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Application:
WB, IHC, ELISA
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express SMAD3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express SMAD3.
Immunogen:
Synthesized peptide derived from human Smad3 around the phosphorylation site of S208. Location: 150-230aa.
Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-SMAD3 (OASG06703) antibody
Target Post-Translational Modification:
Phospho-Ser208
Specificity:
Phospho-Smad3 (S208) Polyclonal Antibody detects endogenous levels of Smad3 protein only when phosphorylated at S208.
Isotype:
IgG
Application Info:
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

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