Catalog No: OASL01085
Size:50ul
Price: $269.00
SKU
OASL01085
Availability: Domestic: within 2 week delivery | International: 2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for OASL01085
Product Info
Predicted Species ReactivityMouse, Rat
Product FormatLiquid. PBS with 0.02% sodium azide, 100 ug/ml BSA and 50% glycerol.
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationWB
Additional InformationBackground: This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin.
::Positive Tissue: Heart, muscle, liver
Reconstitution and StorageStore at -20C for one year. Avoid repeated freeze/thaw cycles.
ImmunogenKLH conjugated Synthetic peptide corresponding to human smad2 around the phosphorylation site of Ser425
PurificationAffinity purification
Target Post-Translational ModificationPhospho-S425
Application InfoWB: 1:500 - 1:1000
Gene SymbolSmad2
Alias SymbolsSMAD2, JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD family member 2
Protein NameMothers against decapentaplegic homolog 2
Uniprot IDO70436, Q15796, Q62432
Molecular Weight52 kDa
  1. What is the species homology for "Smad2 (Phospho-S425) Antibody (OASL01085)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Mouse, Rat".

  2. How long will it take to receive "Smad2 (Phospho-S425) Antibody (OASL01085)"?

    This item is available "Domestic: within 2 week delivery | International: 2 weeks".

  3. What buffer format is "Smad2 (Phospho-S425) Antibody (OASL01085)" provided in?

    This item is provided in "Liquid. PBS with 0.02% sodium azide, 100 ug/ml BSA and 50% glycerol.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Smad2 (Phospho-S425) Antibody (OASL01085)"?

    This target may also be called "SMAD2, JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD family member 2" in publications.

  5. What is the shipping cost for "Smad2 (Phospho-S425) Antibody (OASL01085)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Smad2 (Phospho-S425) Antibody (OASL01085)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Smad2 (Phospho-S425) Antibody (OASL01085)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "52 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Smad2 (Phospho-S425) Antibody (OASL01085)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "Smad2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "Smad2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "Smad2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "Smad2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "Smad2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "Smad2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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